Implications of direct-to-consumer whole-exome sequencing in South Africa
نویسندگان
چکیده
منابع مشابه
Implications of direct-to-consumer whole-exome sequencing in South Africa.
This editorial examines a number of vitally important ethical, legal and scientific concerns that have to be addressed to ensure proper and ethical implementation of direct-to-consumer whole-exome sequencing in South Africa. Individuals taking part in this endeavour must be fully informed of the positive and negative sequelae.
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Introduction Next-generation DNA sequencing empowers scientists to identify genetic variations associated with human disease at higher resolution and greater sensitivity than previously possible. Two approaches are commonly employed -exome sequencing and whole genome sequencing. Exome sequencing targets protein-coding regions comprising approximately 1% of the human genome, while whole genome s...
متن کاملWhole exome and whole genome sequencing.
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ژورنال
عنوان ژورنال: South African Medical Journal
سال: 2016
ISSN: 2078-5135
DOI: 10.7196/samj.2016.v106i2.10534